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Spa therapy is used in the treatment of various diseases and mainly osteoarthritis. Knee osteoarthritis is a very common rheumatic disease whose prevalence increases with longer life span and is a public health problem.
The Forestier and al. study highlighted the actual benefit and confirmed the improvement of the quality of life and pain of the knee osteoarthritis patients from 6 months of spa treatment.[1] A significant decrease of 30% in the rate of Serum Hyaluronic Acid at 6 months after the end of the spa therapy was also highlighted in the Canteloup et al study.[6] This study aims to measure different osteoarticular biomarkers (hyaluronic acid, coll2-1 and CTX1) before, at the end of the spa therapy and 6 months after the spa therapy and correlate with the clinical evaluation.
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Inclusion criteria
Patient with knee osteoarthritis defined according to the recommendations of the American College of Rheumatology (ACR):
Patient can come to the final visit at 6 months and living within a perimeter of 30km around Dax.
Patient affiliated to a social security scheme.
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Interventional model
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37 participants in 1 patient group
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Central trial contact
Anne-Hélène BOIVIN; Jérôme DIMET, PharmD
Data sourced from clinicaltrials.gov
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