Follow-up of Ovarian Function in Young Women Who Underwent Ovarian Cortex Cryopreservation

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status: Completed

Conditions: Female Infertility

Treatments: Other: questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT02454829

CRYOFONOV01

Details and patient eligibility

About

Evaluation of ovarian function by a questionnaire and by medical file analysis of women and girls who underwent ovarian cortex cryopreservation for fertility preservation between 1997 an 2013 in the investigators' institution in order to evaluate their residual ovarian function. A second part of the questionnaire concerns these women's satisfaction regarding the procedure.

Full description

Between 1997 and december 2013, 546 girls and women underwent ovarian cortex cryopreservation in the investigators' institution for fertility preservation. The main indications were the need for a gonadotoxic treatment, repeated ovarian surgery and a genetic risk for premature ovarian failure . These women will be sent a questionnaire concerning their ovarian function since the procedure and a questionnaire about their satisfaction concerning the procedure. Six different questionnaires will be used adapted to the patient's initial indication for cryopreservation and the patient's age at the time of cryopreservation. Complementary data will be obtained by medical file analysis and by contacting the patient's family doctor or gynecologist.

Data will be correlated with received gonadotoxic treatment and surgical interventions.

The purpose of the study is to improve the indications and patient selection for ovarian cortex cryopreservation.

Enrollment: 546 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• women who underwent ovarian cortex cryopreservation in our institution between 1997 and 2013

Exclusion criteria

• deceased women in this cohort

Trial design

546 participants in 6 patient groups

Adults, gonadotoxic treatment

Description:

Women 18 years of age or older who underwent ovarian cortex cryopreservation before gonadotoxic treatment (chemotherapy, radiotherapy)

Treatment:

Other: questionnaire

Girls, gonadotoxic treatment

Description:

Girls under 18 years of age who underwent ovarian cortex cryopreservation before gonadotoxic treatment (chemotherapy, radiotherapy)

Treatment:

Other: questionnaire

Adults, ovarian pathology

Description:

Women 18 years of age or older who underwent ovarian cortex cryopreservation for an ovarian pathology not requiring gonadotoxic treatment but surgery

Treatment:

Other: questionnaire

Girls, ovarian pathology

Description:

Girls under 18 years of age who underwent ovarian cortex cryopreservation for an ovarian pathology not requiring gonadotoxic treatment but surgery

Treatment:

Other: questionnaire

Adults, genetic disorders

Description:

Women 18 years of age or older who underwent ovarian cortex cryopreservation in the context of a genetic risk of premature ovarian failure

Treatment:

Other: questionnaire

Girls, genetic disorders

Description:

Girls under 18 years of age who underwent ovarian cortex cryopreservation in the context of a genetic risk of premature ovarian failure

Treatment:

Other: questionnaire