Follow-up of the Nasal Microbiome and Viral Infections in Newborns Hospitalised in Neonatology. (NEOBIOME)

Caen University Hospital

Status: Completed

Conditions: Microbial Colonization; Neonatal Infection; Viral Infection

Treatments: Diagnostic Test: Nasal swab

Study type: Interventional

Funder types: Other

Identifiers

NCT05717283

2022-A01965-38

Details and patient eligibility

About

The goal of this interventional study is to learn about nasal microbiome and viral infections in newborns hospitalised in neonatology.

The main questions it aims to answer are :

• how often are newborns infected by viruses in neonatology ?
• how does the microbiome develop during first weeks of life ?
• how does microbiome and viruses interacts together ?
• is there a link between viral infection, microbiome, and medical complications during hospitalisation in neonatology ? Participants will have a nasal swab taken each week during their hospitalisation in neonatology, and researchers will take medical data from the medical chart.

Enrollment: 38 patients

Sex: All

Ages: Under 48 hours old

Volunteers: No Healthy Volunteers

Inclusion criteria

• newborn hospitalised in neonatal intensive care unit during the inclusion period
• parents have been informed about the study (speaking french) and have signed the informed consent.
• affiliated to the social security system.

Exclusion criteria

• parental refusal
• minor parents or under judicial protection
• newborn who already have been discharded home before inclusion
• hospitalisation after the first 48 hours of life
• only palliative care

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)