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Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients

S

Somogy Megyei Kaposi Mór Teaching Hospital

Status

Completed

Conditions

Multiple Sclerosis, Primary Progressive
Multiple Sclerosis, Chronic Progressive

Treatments

Other: Spinning grp
Other: Balance
Other: PNF
Other: Training groupe

Study type

Interventional

Funder types

Other

Identifiers

NCT04550650
IKEB2020/08

Details and patient eligibility

About

Different therapies can improve clinical and motor symptoms of multiple sclerosis (MS) similarly, but studies comparing the effects of different exercise therapies on clinical and motor outcomes are scant. We compared the effects of exergaming (EXE), balance (BAL), cycling (CYC), proprioceptive neuromuscular facilitation (PNF), and a standard care wait-listed control group (CON) on clinical and motor symptoms and quality of life (QoL) in people with MS (PwMS).

Methods: PwMS (n = 68, 90% female; age, 47.0 yr; Expanded Disability Status Scale score 5-6) were randomized into five groups. Before and after the interventions (five times a week for 5 wk), PwMS were tested for MS-related clinical and motor symptoms (Multiple Sclerosis Impact Scale-29 (MSIS-29), primary outcome), QoL (EuroQol Five Dimensions Questionnaire), symptoms of depression, gait and balance ability (Tinetti Assessment Tool), static and dynamic balance and fall risk (Berg Balance Scale), walking capacity (6-min walk test), and standing posturography on a force platform.

Patients were followed up for 2 years after 5 weeks of intensive care. Tests are performed every six months.

Enrollment

4 patients

Sex

All

Ages

35 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Multiple Sclerosis
  • instability problem

Exclusion criteria

• Severe heart problems, severe demeanor, alcoholism, drug problems

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

4 participants in 5 patient groups

Controll
No Intervention group
Description:
No intervention
Training grp
Experimental group
Description:
Neurorehabilitation 2 years long intervention, administered daily, targeted postural instability, balance and mobility using at-limit intensity sensorimotor and visuomotor agility training
Treatment:
Other: Training groupe
PNF
Experimental group
Description:
2 years long, You have only treated patients with the PNF technique.
Treatment:
Other: PNF
Spinning group
Experimental group
Description:
Patients developed endurance for 2 years. They worked using a spinning bike.
Treatment:
Other: Spinning grp
Balance
Experimental group
Description:
Neurorehabilitation 2 years long intervention, administered daily, targeted postural instability, balance
Treatment:
Other: Balance

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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