Foot Perfusion by Dynamic Contrast Enhanced MRI in Patients With Peripheral Artery Disease

Fudan University

Status: Not yet enrolling

Conditions: Perfusion; Peripheral Arterial Disease

Treatments: Diagnostic Test: DCE MRI

Study type: Observational

Funder types: Other

Identifiers

NCT06525415

2024ZW001

Details and patient eligibility

About

We investigate the peri-operative foot perfusion through dynamic contrast enhanced MRI in patients with peripheral artery disease

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 to 80 years old;
• PAD patients with Fontaine grade II-IV or Rutherford grade 2-6 and underwent a successful revascularization;
• Patients completed both pre- and post-operative MRI workups;
• Patients signed the informed consent form and be able to complete the clinical follow-up for 1 months.

Exclusion criteria

• Patients has participated in other clinical studies;
• Patients with Heart failure (NYHA III/IV)/right to left shunt heart disease/ severe aortic and mitral insufficiency/acute coronary syndrome/malignant arrhythmia/severe pulmonary hypertension (pulmonary artery pressure at least 90 mmHg)/moderate to severe renal insufficiency (creatinine clearance rate<60 ml/min)
• Any allergic constitution;
• Pregnancy and childbirth;
• Life expectancy<12 months.

Trial design

30 participants in 1 patient group

PAD group

Description:

patients of peripheral artery disease who underwent endovascular treatment

Treatment:

Diagnostic Test: DCE MRI