Force Enhancement of Musculus Quadriceps Femoris During and After Excentric Muscle Activity in Vivo

German Research Foundation

Status: Unknown

Conditions: Healthy; Muscle Quadriceps Femoris

Treatments: Other: muscle activation

Study type: Observational

Funder types: Other

Identifiers

NCT00690547

DFG27112007

Details and patient eligibility

About

Force enhancement (FE) describes the phenomenon of strength potentialization of a muscle cell or the complete muscle during and after active extension compared to the strength of an isometric contraction with same muscle length. The underlying physiological mechanism of this phenomenon is not completely known today. In vitro trials indicate that the interaction of an active and a passive component on the cellular level are responsible for the higher strength measurements. So far FE could be shown in vitro and in vivo on muscle fibers and small human muscles. Further research is needed for verification of the existence of FE in voluntary motor activity in everyday life. In order to approach this objective the investigators will scrutinize the functionality of the deliberately activated musculus (m) quadriceps femoris during and after active extension on the basis of in vivo studies.

Full description

The research proposal is resubmitted with no amendments made regarding content.

Enrollment: 60 estimated patients

Sex: Male

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Males without previous muscular or neurophysiological diseases
• Age between 20 and 40 years

Exclusion criteria

• Previous muscular or neurophysiological diseases

Trial design

60 participants in 1 patient group

Test Group

Treatment:

Other: muscle activation