Forced Oscillation Versus Spirometry in Diagnosing Post Pulmonary Transplant Bronchiolitis Obliterans Syndrome (OSCILLOPOUMON)

Hopital Foch

Status: Completed

Conditions: Bronchiolitis Obliterans Syndrome

Treatments: Other: Forced oscillation

Study type: Interventional

Funder types: Other

Identifiers

NCT01807975

2010/56

Details and patient eligibility

About

A study to evaluate the role of forced oscillation in precocious diagnosis of bronchiolitis obliterans syndrome in patients with pulmonary transplant (time difference in detecting distal airways functional impairment by forced oscillation and the standard technique using spirometry).

Enrollment: 110 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of more than 18 year-old.
• Patients with cardiopulmonary transplant or bilateral lung transplant.
• Clinically stable patients

Exclusion criteria

• Patients already diagnosed with bronchiolitis obliterans.
• Respiratory infection.
• Acute graft rejection.
• Mechanical complications (bronchial dehiscence, pneumothorax, pleural effusion).
• Iatrogenic pneumopathy.
• Inability to perform Respiratory function test.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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110 participants in 1 patient group

post allogreffe patients

Experimental group

Description:

Functional evaluation of distal airway by forced oscillation technique : relevance earlier diagnostic of pulmonary syndrom of oblitérant bronchiolit in post allogreffe patients

Treatment:

Other: Forced oscillation