Forced Oscillations for Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation (OSCILLOMOELL)

Hopital Foch

Status: Completed

Conditions: Bronchiolitis Obliterans; Bone Marrow Transplantation

Treatments: Other: Forced oscillations measure

Study type: Interventional

Funder types: Other

Identifiers

NCT02902471

2010/48

2010-A01229-30 (Other Identifier)

Details and patient eligibility

About

A study to evaluate the role of forced oscillations in diagnosis of bronchiolitis obliterans syndrome in patients after bone marrow transplantation. The force oscillations technique will be compared with classical spirometry.

Enrollment: 110 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients over 18 years
• Bone marrow or hematopoietic stem cells transplantation for more than 100 days
• Clinical stability
• Patients affiliated to a social security system
• Patients having given his (her) written consent.

Exclusion criteria

• Bronchiolitis Obliterans already diagnosed
• Unresolved Respiratory infection
• Unresolved mechanical complication (pneumothorax, effusions)
• Medicinal pneumopathy
• Inability to perform pulmonary function tests

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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110 participants in 1 patient group

Group A

Experimental group

Description:

Patients with bronchiolitis obliterans syndrome after bone marrow transplantation

Treatment:

Other: Forced oscillations measure