Formulated PSTA Injection Versus PATA Alone in the Management of Macular Edema Secondary to Non-ischemic Retinal Vein Occlusions

Al-Azhar University

Status: Completed

Conditions: Macula Edema

Treatments: Drug: Triamcinolone Acetonide alone; Drug: Triamcinolone Acetonide and sodium hyaluronate and chondroitin sulfate

Study type: Interventional

Funder types: Other

Identifiers

NCT05385562

PSTA and macular edema

Details and patient eligibility

About

The aim of this study is to compare formulated Posterior Subtenon Triamcinolone acetonide (PSTA) injection versus Posterior Subtenon Triamcinolone acetonide alone in the management of macular edema secondary to non-ischemic retinal vein occlusions, either central or branch.

Enrollment: 78 patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diminution vision due to macular edema secondary to non-ischemic retinal vein occlusions, either central or branch, as evidenced by clinical and angiographic evaluation
• CMT ≥ 250 µ.
• Willing to participate in the study

Exclusion criteria

• Unwilling to participate in the study.
• Ischemic RVO
• Prior laser treatment
• Glaucoma/Ocular Hypertension
• Cataract which lead to difficulty in the evaluation of macula
• Vitreous hemorrhage
• Macular ischemia
• Iris neovascularisation
• patients with intravitreal injection of anti VEGFs, steroid, or any intraocular surgery 3 months prior to the inclusion.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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78 participants in 2 patient groups

Formulated Posterior Sub Tenon Triamcinolone

Active Comparator group

Treatment:

Drug: Triamcinolone Acetonide and sodium hyaluronate and chondroitin sulfate

Posterior Sub Tenon Triamcinolone alone

Active Comparator group

Treatment:

Drug: Triamcinolone Acetonide alone