Formulation and Efficacy of Exercise Prescription for Patients With Coronary Heart Disease

Jing Ma

Status: Unknown

Conditions: Coronary Heart Disease

Treatments: Behavioral: High intensity exercise prescription; Behavioral: Moderate intensity exercise prescription

Study type: Interventional

Funder types: Other

Identifiers

NCT04923711

2021-249

Details and patient eligibility

About

The purposes of this study is to standardize the process of formulating exercise prescriptions for coronary heart disease（CHD）, verify the safety and effectiveness of exercise prescriptions, and establish a database of exercise prescriptions for CHD, with a view to providing new solutions for cardiac rehabilitation.

Full description

This study conducted a comparative study on the therapeutic effect and safety of exercise prescriptions for patients with coronary heart disease with different risk stratifications. The purposes of this study is to standardize the process of formulating exercise prescriptions for coronary heart disease（CHD）, verify the safety and effectiveness of exercise prescriptions, and establish a database of exercise prescriptions for CHD, with a view to providing new solutions for cardiac rehabilitation.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18-80 years old with a diagnosis of coronary heart disease，NYHA class I-III HF patients.

Exclusion criteria

• acute myocardial infarction within 2 weeks
• Uncontrolled tachycardia (heart rate at rest >120bpm
• Uncontrolled polypnea（breath rate at rest >30 breath per minute
• Uncontrolled respiratory failure （SPO2 ≤90%）
• Uncontrolled hyperglycemia (Random blood glucose>18mmol/L)
• Uncontrolled malignant arrhythmia with hemodynamic instability
• Uncontrolled septic shock and septicopyemia
• Uncooperation of the patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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200 participants in 2 patient groups

Moderate Intensity Group

Experimental group

Description:

Group received a moderate exercise prescription of moderate intensity

Treatment:

Behavioral: Moderate intensity exercise prescription

High Intensity Group

Experimental group

Description:

Group received a moderate exercise prescription of high intensity

Treatment:

Behavioral: High intensity exercise prescription