Foveal Cone Outer Segment Resumption to Predict Visual Recovery After Macular Hole Surgery

Kyorin University

Status: Completed

Conditions: Macular Holes

Treatments: Procedure: Vitreous surgery for macular hole

Study type: Interventional

Funder types: Other

Identifiers

NCT01381965

KYORIN-H21012 (Other Identifier)

Kyorineye006

Details and patient eligibility

About

Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.

Full description

Spectral domain optical coherence tomography (SD-OCT) was used to calculate the mean length of photoreceptor cone outer segment tips (COST) defect on 1, 3, 6, 9, and 12 months after macular hole surgery. The correlation between the mean length of COST defect and the BCVA was determined. Prognostic factors might have influenced for COST repair was also evaluated by multivariable analysis.

Enrollment: 72 patients

Sex: All

Ages: 20 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• macular hole patients with surgically-closed hole

Exclusion criteria

• macular hole patients failed to close hole
• presence of retinal diseases including a treated rhegmatogenous retinal detachment, diabetic retinopathy, and high myopia with an axial length >27.0mm or refractive error > -8.0 diopters(D).
• patients who were not followed at least 6 months

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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72 participants in 1 patient group

Eyes with macular hole

Active Comparator group

Treatment:

Procedure: Vitreous surgery for macular hole