Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars

Yasmine Ahmed Abd El-Maguid El-Hadidy

Status and phase: Unknown; Early Phase 1

Conditions: Atrophic Acne Scar

Treatments: Combination Product: Fractional laser with PRP fluid or PRP gel

Study type: Interventional

Funder types: Other

Identifiers

NCT04580758

Kasr El Aini Hospital

Details and patient eligibility

About

This study is to test the efficacy of fractional laser combined with either PRP fluid or PRP gel in the treatment of atrophic acne scars

Full description

The study will include 20 patients, treated with fractional CO2 laser plus PRP fluid on one side of the face and fractional CO2 laser plus PRP gel on the other side.

Choosing which side of the face will be injected with PRP fluid and which side will be injected with PRP gel will be chosen according to a randomization table for each patient.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age above 18
• Both genders
• Skin types III - V
• Willingness and ability to comply with the requirements of the protocol
• Atrophic acne scars

Exclusion criteria

• Patients with active acne
• Patients with herpes labialis, bacterial infections, other infections such as HBV. HCV or HIV.
• Oral isotretinoin use in the previous 6 months
• Pregnancy
• Tendency to keloid formation
• Patients with severe systemic illness or malignancy
• Patients with connective tissue diseases
• Patients with bleeding tendencies or any other hematological disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Fractional laser with PRP fluid

Active Comparator group

Description:

Fractional CO2 laser then the PRP is injected afterwards

Treatment:

Combination Product: Fractional laser with PRP fluid or PRP gel

Fractional laser with PRP gel

Active Comparator group

Description:

Fractional CO2 laser then the PRP gel is injected afterwards

Treatment:

Combination Product: Fractional laser with PRP fluid or PRP gel