Fractional Laser and Steroid Ointment to Improve the Old Scar After Thyroidectomy

Chang Gung Medical Foundation

Status: Completed

Conditions: Thyroid; Wound; Steroid Acne

Treatments: Device: Laser-assisted drug delivery

Study type: Interventional

Funder types: Other

Identifiers

NCT04719559

201800241A3

Details and patient eligibility

About

This clinical study was conducted to assess the effects of LADD combined with a fractional ablative carbon dioxide laser and a topical steroid for the treatment of post-thyroidectomy hypertrophic scars.

Full description

Thyroidectomy results in unsightly scarring at the anterior neck of the patient. A clinical study was conducted to assess the effectiveness of five courses, applied every 4 weeks, of laser-assisted drug delivery (LADD) combining a fractional ablative carbon dioxide laser and topical 0.05% clobetasol propionate to the treatment of post-thyroidectomy hypertrophic scars in patients. Assessments of the scars by the patient themselves according to the patient and observer scar assessment scale.

Enrollment: 10 patients

Sex: All

Ages: 20 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients had presented a persistent hypertrophic scar at the neck region for more than 1 year after their thyroidectomy.

Exclusion criteria

• Systemic chronic disease or a history of autoimmune disease or human immunodeficiency virus infections.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Post-Thyroidectomy Hypertrophic Scar

Other group

Description:

Patients had all presented a persistent hypertrophic scar at the neck region for more than 1 year after their thyroidectomy.

Treatment:

Device: Laser-assisted drug delivery