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Frailty as a Predictor of Neurosurgical Outcomes in Brain Tumor Patients

University of Colorado Denver (CU Denver) logo

University of Colorado Denver (CU Denver)

Status

Completed

Conditions

Brain Tumors

Study type

Observational

Funder types

Other

Identifiers

NCT02530749
14-0579

Details and patient eligibility

About

Frailty as an adjunct to preoperative assessment of neurosurgical patients has never been evaluated. This study aims to determine if frailty predicts neurosurgical complications in brain tumor patients and enhances current perioperative risk models.

Full description

Preoperative risk assessment is important, but inexact, in older patients because physiologic reserves are difficult to measure. This also makes an important difference related to brain tumor patients, who may be burdened with systemic disease, alterations in cognition, or affected by other comorbidities. When assessing quality of life for brain tumor patients, having a better predictor of postsurgical outcome would be beneficial in appropriately counseling these patients. Frailty is thought to estimate physiologic reserves, and its use has been found to predict postoperative complications, length of stay, and discharge to a skilled or assisted-living facility in neurosurgical patients. Frailty as an adjunct to preoperative assessment of neurosurgical patients has never been evaluated. This study aims to determine if frailty predicts neurosurgical complications in brain tumor patients and enhances current perioperative risk models.

Enrollment

265 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adult
  • Ambulatory (able to walk)
  • Scheduled for neurosurgical resection of brain tumor

Exclusion criteria

  • Parkinson disease
  • Previous stroke
  • Taking: carbidopa/levodopa, donepezil hydrochloride, or antidepressants

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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