Frailty in Older HIV-infected Individuals

The Chinese University of Hong Kong

Status: Enrolling

Conditions: HIV Infections

Study type: Observational

Funder types: Other

Identifiers

NCT03413683

Geri_HIV protocol v1 03Nov2017

Details and patient eligibility

About

Frailty has been proposed as a measure of biological (as opposed to chronological) aging. In this study the investigators plan to: (1) measure frailty in a cohort of older HIV-infected individuals in Hong Kong, and its association with mortality and quality of life; (2) identify risk factors predictive of development of frailty in HIV-infected individuals in Hong Kong; and (3) determine the outcomes of HIV-infected individuals in Hong Kong with and without frailty.

The following assessment will be done:

1. Physical examination including measuring height, weight, hip and waist circumference.
2. Grip strength, chair stand test, gait speed test, balance tests, and neurocognitive tests
3. Geriatric syndromes, screening for depression, disability and quality of life.
4. Blood tests during fasting state to measure metabolic parameters.

This is a prospective longitudinal observational study that lasts for 10 years.

Enrollment: 100 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV infection with positive anti-HIV antibody
• Age ≥50 years

Exclusion criteria

• Refuses to consent