Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients

University of Sao Paulo General Hospital

Status: Enrolling

Conditions: Physical Disability; Fragility; Chronic Thromboembolic Pulmonary Hypertension

Study type: Observational

Funder types: Other

Identifiers

NCT06286891

CAAE: 73520523.7.0000.0068

Details and patient eligibility

About

The goal of this observational and prospective study is to investigate changes in physical performance, lung function, respiratory and peripheral muscle strength in patients during the postoperative period following pulmonary endarterectomy (PET).

Full description

This study aims to investigate the physical changes in patients undergoing pulmonary endarterectomy (PET). It will observe alterations in physical performance, lung function, and muscle strength during the postoperative period. This study, observational and prospective, will include individuals aged ≥18 scheduled, evaluating them preoperatively, post-intensive care unit discharge, before hospital discharge and after six months . Assessments involve tests like the Six-minute walk test, Short Physical Performance Battery, One-minute sit-to-stand test, manovacuometry, dynamometry, spirometry and Clinical Frailty Scale to identify frailty and measure muscle and lung function. The study also aims to explore predictive variables for functional loss during hospitalization.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Both genders
• Elective pulmonary endarterectomy surgery
• Absence of cognitive or peripheral motor impairment that prevents the performance of functional tests in the preoperative period.

Exclusion criteria

• Reoperation for any reason
• Presence of cognitive or peripheral motor impairment that prevents the performance of functional tests in the postoperative period.