Frailty Score Assessment for Elderly Patients Undergoing Cardiac Resynchronization Therapy (FRAILTY)

Centre Hospitalier Universitaire, Amiens

Status: Completed

Conditions: Heart Failure

Treatments: Other: Frailty

Study type: Observational

Funder types: Other

Identifiers

NCT02369419

RNI2013-02-DR-KUBALA

Details and patient eligibility

About

Background: The cardiac resynchronization therapy (CRT) has been shown to improve symptoms and outcome of patients with congestive heart failure (HF), and depressed left ventricular ejection fraction (LVEF < 35 %). The rate of non-responders to CRT is estimated at 30 %. Yet, the impact of frailty on the response to CRT has not been studied, until now.

Purpose : To assess the impact of frailty in the elderly, on the response to CRT.

Full description

Methods : Frailty is evaluated before implant ,and defined as <14/17 points using the ONCODAGE score, in 150 patients of > 70 years age, selected for CRT according to the ESC 2013 guidelines. The response to CRT, estimated at 9 months, is defined as an improvement of at least 5 % of the LVEF and the absence of HF hospitalization or cardiovascular death.

Enrollment: 150 patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of > 70 years age,
• Selected for CRT according to the ESC 2013 guidelines

Exclusion criteria

• patients included in other clinical trial which can interfere with the results of this one

Trial design

150 participants in 1 patient group

CRT

Description:

Patients over 70 years age, selected for CRT according to the ESC 2013 guidelines.

Treatment:

Other: Frailty