Free Gingival Graft Adjunct With Low Level Laser Therapy

Abant Izzet Baysal University

Status: Completed

Conditions: Transplants; Low-Level Light Therapy; Gingival Recession, Localized; Wounds and Injuries

Treatments: Other: Clinical examination; Device: CheseeTM Diode Laser

Study type: Interventional

Funder types: Other

Identifiers

NCT03425695

AIBU

Details and patient eligibility

About

The present placebo-controlled parallel design clinical study was planned to determine the effect of low level laser therapy on clinical periodontal conditions and dimensions of free gingival graft as well as postoperative pain levels in the surgical area.

Full description

Background: Shrinkage of the free gingival graft (FGG) and patient's discomfort during healing period are important concerns. Therefore, this study aimed to evaluate the effect of low level laser therapy (LLLT) in terms of enhancing wound healing, reducing graft shrinkage and postoperative pain.

Methods: Thirty patients were randomly assigned to receive either FGG+ LLLT (test, n = 15) or FGG + placebo LLLT (control, n = 15). In the test group, a diode laser (aluminum-gallium-arsenide, 810 nm, 0.1 W, continuous mode, time of irradiation:60 s, energy density: 6 J/cm2, spot size:0.5 cm) was applied immediately after the FGG surgery and 1,3,7, and 14 days later. The control group received the same sequence of irradiation with the laser-off. Comparison of the graft surface areas between groups at 1st, 3rd and 6th months were made with an image-analyzing software. Complete wound epithelization, visual analogue scale (VAS) pain score of recipient site and the number of analgesic used were evaluated after the surgery.

Enrollment: 30 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients >18 years old
• Patients presenting Class I or II Miller gingival recession on vital incisors in the mandibular anterior region with no caries or restoration
• The included teeth had also keratinized gingiva <2 mm; PI and GI<1.
• The patients had to be systemically healthy and non-smokers.

Exclusion criteria

• Patients presenting active periodontal disease and probing depth >3 mm; taking medications that would interfere with the wound-healing process or that contraindicate the surgical procedure;
• Pregnant or lactating women;
• Patients who underwent periodontal surgery in the study area;
• Patients with orthodontic therapy in progress were excluded.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups, including a placebo group

Test group

Experimental group

Description:

Free Gingival Graft (FGG) + Low Level Laser Therapy (LLLT) + Clinical Examination The test group received LLLT with a diode laser (CheseeTM Diode Laser, Wuhan, China ) at the FGG sites with a wavelength of 810 nm and output power of 0.1 W, for 60 s, with an energy density of 6 J/cm2 in the continuous wave mode (spot size:0.5 cm). The laser beam was directed perpendicularly toward the tissue in the noncontact mode. The laser was irradiated at the recipient sites immediately after surgery and 1, 3, 7, and 14 days later.

Treatment:

Other: Clinical examination

Device: CheseeTM Diode Laser

Control group

Placebo Comparator group

Description:

Free Gingival Graft (FGG)+Placebo Low Level Laser Therapy (PLLLT) + Clinical Examination The control group received PLLLT with a diode laser (CheseeTM Diode Laser, Wuhan, China ) same as test group without pushing the start button

Treatment:

Other: Clinical examination

Device: CheseeTM Diode Laser