Freeze All on Oocyte Maturatin by Gonadotropin Agonist Versus Human Chorionic Gonadotroipin

Aljazeera Hospital

Status: Unknown

Conditions: Infertility

Treatments: Drug: HCG ( eg. Choriomon ); Drug: Agonist (decapeptyl )

Study type: Interventional

Funder types: Other

Identifiers

NCT04749979

Oocyte

Details and patient eligibility

About

Estradiol valerate in the form of cycloprogenova™ (white tablet only) was started on day 2 or 3 of cycle with oral dose 4 mg divided on 2 doses in addition to Aspocid 75 mg once daily with folic acid 500 mcg once daily.

Full description

U/S was done on day 9 or 10 of cycle to assess endometrial thickness, then every other day until endometrial thickness of 8 mm or more is reached and when endometrial thickness reaches 8 mm or more FET was planned. Progesterone in the form of prontogest™ 400 mg vaginal suppository twice dTwo to Four Day 5 Embryos was transferred

Enrollment: 100 estimated patients

Sex: Female

Ages: 18 to 42 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• PCOS patients according to Rotterdam criteria
• Female age between 20 and 40 years.
• Primary or secondary infertility.
• Body mass index (BMI) between 18 and 40 kg/m2.

Exclusion criteria

• Ovarian endometriosis.

  • Ovarian cysts before induction.
  • Known uncontrolled endocrinal abnormalities (like hypo or hyperthyroidism)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

giving agonist ( eg. decapeptyl )

Active Comparator group

Description:

Giving women agonist

Treatment:

Drug: Agonist (decapeptyl )

Giving HCG (eg. choriomon )

Active Comparator group

Description:

Giving women HCG

Treatment:

Drug: HCG ( eg. Choriomon )