Freezing in Parkinson's Disease (parkinson)

Necmettin Erbakan University

Status: Completed

Conditions: Parkinson Disease

Treatments: Other: Visual & Auditory Cueing Walker

Study type: Interventional

Funder types: Other

Identifiers

NCT07212205

Necmettin Erbakan university (Other Identifier)

nezahat keleşoğlu

Details and patient eligibility

About

The aim of this study was to investigate the effects of a visual and auditory cueing walker on freezing of gait during walking in patients with Parkinson's disease (PDF), compared to Parkinson patients without freezing of gait (PDNF).Sample size was calculated to detect a difference of 0.37 m/sec on mean velocity, with a deviation of 0.3 m/sec, two-sided 5% significance level, and power of 90%. Considering the expected 10% dropout rate, twelve subjects were included.Researcher R1 determined whether the subject was eligible for inclusion in the trial and researcher R2 carried out the gait analysis. Both examiners were unaware of group allocation. An independent researcher (R3) performed the clinical evaluation before the procedures started. Participants walked back and forth on a 7-meter walking path under two different conditions: without cues and with a walker providing visual and auditory cues. To assess the risk of falls in both groups, the "Tinetti Balance and Gait Assessment" was conducted. Additionally, the "Dynamic Gait Index" was used to evaluate the ability to adapt walking to varying task demands, and the Timed Up and Go Test (TUGT) was employed to determine walking speed.

Full description

This study suggests that a walker providing visual and auditory cues may improve daily walking in patients with Parkinson's disease with freezing of gait (PDF) and reduce the risk of falls in patients with Parkinson's disease without freezing of gait (PDNF) who exhibit hypokinetic gait patterns.

Enrollment: 30 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Those with a Hoehn-Yahr classification between 2.5 and 4 were included in the study.

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Exclusion Criteria:Patients with secondary parkinsonism, severe systemic diseases, psychiatric illness, cognitive impairment (Mini-Mental State Examination score <24), hearing and vision loss, musculoskeletal problems, or symptoms suggestive of cerebellar dysfunction were excluded from the study.

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Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

PDF (Parkinson's Disease with Freezing of Gait)

Experimental group

Description:

Intervention Name: Visual \& Auditory Cueing Walker Description: "Participants in this arm were assessed under two within-subject conditions: walking on a 7-meter path without cues (control condition) and walking on the same path using a visual and auditory cueing walker (intervention condition). Each participant completed both conditions in a single session. Pre- and post-walking evaluations were conducted for walking speed (Timed Up and Go Test), fall risk (Tinetti Balance and Gait Assessment), and gait adaptation (Dynamic Gait Index). The 'no cues' condition represents a repeated-measures control within the same arm. Participants were included based on the presence of freezing of gait." Planned Enrollment: 18

Treatment:

Other: Visual & Auditory Cueing Walker

PDNF (Parkinson's Disease without Freezing of Gait)

Experimental group

Description:

Intervention Name: Visual \& Auditory Cueing Walker Description: "Participants in this arm were assessed under two within-subject conditions: walking on a 7-meter path without cues (control condition) and walking on the same path using a visual and auditory cueing walker (intervention condition). Each participant completed both conditions in a single session. Pre- and post-walking evaluations were conducted for walking speed (Timed Up and Go Test), fall risk (Tinetti Balance and Gait Assessment), and gait adaptation (Dynamic Gait Index). The 'no cues' condition represents a repeated-measures control within the same arm. Participants were included based on the absence of freezing of gait." Planned Enrollment: 12

Treatment:

Other: Visual & Auditory Cueing Walker