French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis

Hôpital Edouard Herriot

Status: Unknown

Conditions: Quality of Life

Treatments: Procedure: quality of life after different type of surgery; Other: Procedure surgery behavioral and genetic diagnosis

Study type: Observational

Funder types: Other

Identifiers

NCT01987518

Peps Data Base

SISRA (Other Identifier)

Details and patient eligibility

About

French cohorte about polyposis digestive diseases

Full description

Family Adenomatous Polyposis APC and MYH Genes Peutz Jeghers Disease Cowden Disease Festooned polyposis Juvenile polyposis Hyperplastic polyposis

Enrollment: 350 estimated patients

Sex: All

Ages: 12 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• APC Gene mutation
• MYH Homozygote mutation
• COWDEN Disease with PTEN gene mutation
• Peutz Jeghers Disease with STK 11 gene mutation
• Juvenile polyposis with SMAD 4 gene mutation

Exclusion criteria

• heterozygote MYH Gene Mutation

Trial design

350 participants in 1 patient group

digestive polyposis

Description:

Family adenomatous polyposis (APC or MYH genes) Peutz Jeghers Disease Cowden Disease Festooned Polyposis Juvenile Polyposis Hyperplastic Polyposis

Treatment:

Procedure: quality of life after different type of surgery

Other: Procedure surgery behavioral and genetic diagnosis