French Source-monitoring Task (SOUMO)

Hôpital le Vinatier

Status: Unknown

Conditions: Schizophrenia

Treatments: Other: Questionnaire; Other: Cognitive tests

Study type: Interventional

Funder types: Other

Identifiers

NCT04237155

2019-A02549-48

Details and patient eligibility

About

Source-monitoring is a cognitive process that refers to the ability to remember the source of an information. Source-monitoring processes are usually studied using experimental behavioral tasks. These tasks, which are very heterogeneous, are not all available in French and, for the most part, cannot be used in neuroimaging protocols.

The aim of this project is to develop an experimental task which allows the measurement of source-monitoring performances, and which is adapted to neuroimaging protocols in a French-speaking population.

Full description

The study will include 2 steps: 1) validation of the verbal material necessary for the creation of the source-monitoring task and 2) testing the task.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and Women aged between 18 and 45
• Having given their written informed consent
• Native French speakers
• Normal or corrected-to-normal vision
• Education level greater than or equal to 8 (in years)
• For the healthy control group, no history of previous diagnosed psychiatric disorders (according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders - DSM5), absence of first-degree relatives diagnosed with spectrum disorder schizophrenia and bipolar disorder (DSM).
• For the schizophrenia patients group, meeting the DSM5 criteria for schizophrenia.

Exclusion criteria

• Do not consent to be included in the study
• History of hearing impairments
• People who cannot read
• Presence of neurological or somatic diseases
• Being under tutorship or curatorship

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 4 patient groups

Healthy controls involved in step 1

Other group

Description:

30 healthy individuals will complete a verbal material scoring questionnaire

Treatment:

Other: Questionnaire

Patients with schizophrenia involved in step 1

Other group

Description:

30 patients with schizophrenia will complete a verbal material scoring questionnaire

Treatment:

Other: Questionnaire

Healthy controls involved in step 2

Other group

Description:

30 healthy individuals will complete the source-monitoring task which will be created from step 1 as well as the task of reference

Treatment:

Other: Cognitive tests

Patients with schizophrenia involved in step 2

Other group

Description:

30 patients with schizophrenia will complete the source-monitoring task which will be created from step 1 as well as the task of reference

Treatment:

Other: Cognitive tests