Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application

Laval University

Status: Enrolling

Conditions: One Lung Ventillation (OLV); Acidosis; Thoracic; Hypercapnia; Surgery; Mechanical Ventilation; Smartphone Application

Treatments: Other: one lung ventilation

Study type: Observational

Funder types: Other

Identifiers

NCT07099963

2026-4405

Details and patient eligibility

About

One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.

Full description

The aim of the study is to:

1. Evaluate whether the initial ventilation settings (tidal volume and respiratory rate) during one-lung ventilation are appropriate to prevent respiratory acidosis.
2. Compare the ventilation settings (tidal volume and respiratory rate) made by clinicians with those proposed by an smartphone application ''VentilO''.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults (≥ 18 years old)
• Patients intubated and undergoing one-lung ventilation during thoracic surgery
• Volume-controlled ventilation mode used intraoperatively

Exclusion criteria

• Arterial blood gas data unavailable during one-lung ventilation
• Missing demographic data (sex, height, actual weight)

Trial design

100 participants in 1 patient group

Thoracic surgery

Description:

Patient managed with one lung ventilation

Treatment:

Other: one lung ventilation