Frequency of Metabolic Syndrome in Down Syndrome Patients

Universidad de Guanajuato

Status: Completed

Conditions: Down Syndrome; Metabolic Syndrome X

Study type: Observational

Funder types: Other

Identifiers

NCT00864461

249-08

Details and patient eligibility

About

The aim of this study is to assess the frequency of metabolic syndrome in Down syndrome patients because the prevalence of diabetes mellitus and obesity is higher in individuals with Down syndrome than in the general population.

Enrollment: 96 patients

Sex: All

Ages: 7 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Down syndrome

Exclusion criteria

• History of congenital cardiac defects requiring open-heart surgery
• History of gastroenterologic anomalies requiring bowel resection and/or ongoing medical intervention
• History of leukemia or other cancer
• History of hypothyroidism requiring thyroid hormone replacement

Trial design

96 participants in 2 patient groups

Case

Description:

Patients with clinical and cytogenetics diagnosis of Down syndrome, between 7 - 24 years old.

Control

Description:

Siblings of the same gender of the case, between 7-24 years old.