Frequency of Palpebral Involvement in Adult With Atopic Dermatitis (PAUPIAD)

University Hospital, Lille

Status: Enrolling

Conditions: Atopic Dermatitis

Treatments: Other: Standard dermatology consultation

Study type: Observational

Funder types: Other

Identifiers

NCT04826744

2020_15

2020-A02373-36 (Other Identifier)

Details and patient eligibility

About

Atopic dermatitis is a common inflammatory skin disease, resulting from genetical, immunological and environmental factors. Head and neck are among the most frequent involved areas, almost 50% in adult patients according to most publications. Palpebral involvement is also common and a source of major quality of life impairment for patients.

However, the real frequency of this palpebral involvement is unknown, only estimated about 20% in few studies. The treatment of this location remains difficult, regarding to the thickness of palpebral skin and proximity of the eye.

To our knowledge, no prospective studies about allergological skin tests (such as patch-tests) in atopic patients with palpebral involvement had been conducted.

Finally, atopic dermatitis is frequently associated with ophthalmological diseases such as conjunctivitis, keratoconus or cataract, which belong to the minor criteria of Hanifin and Rakja classification.

A better knowledge of the atopic dermatitis palpebral involvement and the associated factors seems to be needed to improve the treatment and the quality of life of patients

Enrollment: 550 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Atopic Dermatitis according to the revised Hanifin and Rakja criteria (UK Working Party)
• Oral consent
• Valid social insurance

Exclusion criteria

• Personal history of uncontrolled asthma
• No social insurance
• Protective measures
• Age under 18
• Pregnancy or breast-feeding

Trial design

550 participants in 1 patient group

Adults with palpebral involvement of atopic dermatitis

Treatment:

Other: Standard dermatology consultation