Frequency of Ventilator Associated Pneumonia (VAP) in Mechanically Ventilated Patients Using the AnapnoGuard System

Hospitech Respiration

Status: Completed

Conditions: Ventilator Associated Pneumonia

Treatments: Device: routine mechanical ventilator; Device: AnapnoGuard 100,

Study type: Interventional

Funder types: Industry

Identifiers

NCT01126320

HST -AG -02

Details and patient eligibility

About

Ventilator Associated Pneumonia (VAP) is a common complication experienced by mechanically ventilated patients and within the framework of Respiratory Intensive Care Units. The AnapnoGuard system, developed by Hospitech Respiration Ltd. is a ventilation guard system that includes a number of unique characteristics. This study was designed to test the frequency VAP in mechanically ventilated ICU patients using the AnapnoGuard System.

Enrollment: 161 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ICU patients;
• Patient was connected to AnapnoGuard system up to six hours from intubation;
• Age - above 18.

Exclusion criteria

• Pneumonia;
• Aspiration Pneumonia;
• Chronic or Severe Pneumonia;
• Chronic Obstructive Pulmonary Disease (COPD) requiring permanent home-based antibiotic treatment;
• Interstitial Lung Disease (ILD);
• Post Lung Transplant State;
• Immunosuppression.
• Patients ventilated in prone position
• Patient who was ventilated 3 months prior to being enrolled in the study
• Pregnant women

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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161 participants in 2 patient groups

AnapnoGuard 100

Experimental group

Description:

Respiratory guard system during mechanical ventilation

Treatment:

Device: AnapnoGuard 100,

Control

Active Comparator group

Description:

routine mechanical ventilator

Treatment:

Device: routine mechanical ventilator