Fronto-limbic Functional Connectivity Via Real-time fMRI Neurofeedback

University of Electronic Science and Technology of China

Status: Completed

Conditions: Healthy

Treatments: Device: Real-time fMRI neurofeedback from Turbo Brain voyager (TBV) 3.2

Study type: Interventional

Funder types: Other

Identifiers

NCT02692196

UESTC-neuSCAN-09

Details and patient eligibility

About

Real-time fMRI neurofeedback training induced volitional control of brain activity and connectivity could help individuals to gain better control over their emotions.

Full description

In the present proof-of-concept study, investigators plan to evaluate whether real-time fMRI neurofeedback training can enable individuals to gain volitional control over their fronto-limbic circuitry. Given that this circuitry has been abundantly implicated in emotional perception and regulation this could facilitate emotional control. Suitable participants underwent fronto-limbic connectivity feedback training and sham training in a cross over design. During both trainings participants are instructed to regulate the neural indices during feedback. We expect that receiving fronto-limbic feedback enhances emotion regulation during the training.

Enrollment: 24 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

• pregnant, taking oral contraceptives

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 2 patient groups

Neurofeedback Training

Experimental group

Description:

Neurofeedback training - neurofeedback of fronto-limbic functional connectivity.

Treatment:

Device: Real-time fMRI neurofeedback from Turbo Brain voyager (TBV) 3.2

Sham Control

Sham Comparator group

Description:

Sham training - feedback that is not related with fronts-limbic connectivity (motor connectivity)

Treatment:

Device: Real-time fMRI neurofeedback from Turbo Brain voyager (TBV) 3.2