FTO Gene Variants and Diet in Obesity

Hacettepe University

Status: Completed

Conditions: Genetic Predisposition; Diet Habit; Obesity

Study type: Observational

Funder types: Other

Identifiers

NCT04205318

GO15/612-11

Details and patient eligibility

About

Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.

Enrollment: 400 patients

Sex: All

Ages: 24 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

1. attending routine outpatient visits,
2. aged 24 to 50 years,
3. having a BMI ≥ 18.50 kg/m2

Trial design

400 participants in 2 patient groups

study

Description:

obese (BMI ≥25.00 kg/m2, n=200)

control

Description:

non-obese (BMI= 18.50-24.99 kg/m2, n=200)