Full-Thickness-Gastroplication For The Treatment Of Gastroesophageal Reflux Disease GERD

General Public Hospital Zell am See

Status: Unknown

Conditions: Gastroesophageal Reflux Disease

Treatments: Procedure: Full-Thickness-Gastroplication

Study type: Interventional

Funder types: Other

Identifiers

NCT01453985

Zell04

Details and patient eligibility

About

This is a prospective study to extensively evaluate subjective patient parameters on quality of life, reflux-symptoms, side effects, medication-use and measurements of esophageal manometry and Impedance-pH-Monitoring after Full-Thickness-Gastroplication.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• persistent or recurrent symptoms despite continuous medical treatment, at least one typical reflux symptom (heartburn/ regurgitation/dysphagia/epigastric pain) and/or at least one atypical reflux symptom (cough/ asthma/hoarseness/distortion of taste), pathologic esophageal acid exposure as documented by a reflux-related DeMeester score ≥14.7, and symptom correlation ≥50%, and/or reflux episodes >73.

Exclusion criteria

• any distinct hiatal hernia detectable by gastroscopy or barium radiography, dysphagia, esophageal strictures, poor physical status (American Society of Anesthesiologists (ASA) scores III and IV) and pregnancy.

Trial design

0 participants in 1 patient group

Full-Thickness-Gastroplication

Experimental group

Treatment:

Procedure: Full-Thickness-Gastroplication