Full-thickness Skin vs. Synthetic Mesh in the Repair of Large Incisional Hernia

Karolinska Institute

Status: Unknown

Conditions: Postoperative Pain; Ventral Hernia

Treatments: Procedure: Ventral hernia repair using mesh; Procedure: Ventral hernia repair using full thickness skin graft

Study type: Interventional

Funder types: Other

Identifiers

NCT01413412

2009/227-31/3

Details and patient eligibility

About

This is a prospective randomized study to compare surgical methods for the repair of large abdominal hernia.

Full description

Patients with giant (>10 cm in diameter) abdominal wall hernia are included in a prospective randomized study comparing conventional mesh repair with the best possible method to onlay full thickness skin grafts.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ventral hernia > 10 centimeters, abdominal wall pain or discomfort, desire hernia repair.

Exclusion criteria

• < 18 years of age, ongoing pregnancy or nursing, ongoing immunosuppressive treatment,ongoing smoking.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Hernia repair using full-thickness skin graft

Experimental group

Description:

25 patients

Treatment:

Procedure: Ventral hernia repair using full thickness skin graft

Hernia repair using Mesh

Experimental group

Description:

25 patients

Treatment:

Procedure: Ventral hernia repair using mesh