Function and Modulation of Fibulin-1 Assembly in Nucleus of Corneal Fibroblasts

Far Eastern Memorial Hospital

Status: Unknown

Conditions: Function of Mitomycin C in Cornea

Treatments: Drug: Mitomycin C

Study type: Observational

Funder types: Other

Identifiers

NCT01808495

NSC101-2320-B-418-002 (Other Grant/Funding Number)

FEMH-IRB-101002-F

Details and patient eligibility

About

The purpose of this study is to investigate the role of nuclear Fibulin-1 (FBLN1) in Human Corneal Fibroblasts under treatment of mitomycin C (MMC).

Enrollment: 5 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The frozen storage cells in liquid nitrogen were amplified from the residual corneal rim of the donors with more than 20 years old following penetrating keratoplasty.

Exclusion criteria

• The donors were younger than 20 years old.