Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain

KK Women's and Children's Hospital

Status: Withdrawn

Conditions: Endometriosis of Uterus; Pelvis Pain Chronic

Treatments: Other: Functional magnetic resonance imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT02160483

2013/728/D

Details and patient eligibility

About

Functional magnetic resonance imaging in women with chronic pelvic pain using arterial spin labelling, functional connectivity, diffusion tensor imaging and magnetic resonance spectroscopy.

Full description

Multimodal magnetic resonance neuroimaging will be utilised. Arterial spin labelling is tightly coupled with cerebral metabolism and can be used as a marker of neural activity. Resting state magnetic resonance imaging which measures synchronous activity across the brain, allows detection of functional connectivity of intrinsic brain network. Diffusion tensor imaging detects the anisotropic water diffusion in axonal fibres can provide information on connectivity and fibre tracts. Magnetic resonance spectroscopy would enable the levels of neurotransmitter to be elucidated.

Sex: Female

Ages: 21 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic pelvic pain
• Endometriosis

Exclusion criteria

• Contraindication to magnetic resonance imaging

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Magnetic resonance imaging

Experimental group

Description:

Functional magnetic resonance imaging using arterial spin labelling, functional connectivity, diffusion tensor imaging, magnetic resonance spectroscopy to evaluate women with chronic pelvic pain and/ or endometriosis

Treatment:

Other: Functional magnetic resonance imaging