Functional Connectivity In Relation To Proprioception and Sensorimotor Recovery in Stroke Patients (Feasibility Study)

University of Minnesota (UMN)

Status: Completed

Conditions: Stroke

Treatments: Other: Cognitive multisensory rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT02445768

PMR-2015-23168

Details and patient eligibility

About

The purpose now is to:

1. identify brain connections related to proprioception to have a better understanding of differences between people with stroke and healthy persons
2. evaluate how these brain connections will change in people with stroke when they are engaged in 6-week cognitive multisensory rehabilitation.

Enrollment: 43 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Inclusion criteria for healthy subjects are:

• medically stable;
• 18 - 99 years of age;
• able to hear the instructions given during the study

Inclusion criteria for stroke patients are:

• at least 6 months post-stroke;
• medically stable;
• 18 - 99 years of age;
• subcortical or cortical infarct confirmed with MRI;
• Mini-mental State Exam > 24/30 (Folstein et al., 1975);
• able to hear the instructions given during the study;
• able to comprehend the instructions given during the study;
• able to commit time to participate in a 6-12-weeks rehabilitation program

Exclusion criteria

• having ever experienced a stroke or another brain injury or illness related to the brain that has lasting effects or effects experienced at the moment of recruitment;
• severe sensory impairments such that different movements of the finger, hand or wrist are not reliably felt;
• contractures in tested arm that hinder persons from keeping the outstretched arm in a relaxed position;
• interfering comorbidities (e.g. fracture, cancer, peripheral neuropathy);
• exhibit contra-indications to enter the magnetic field of the 3T (pacemakers, metal parts in the body etc);
• pregnant or nursing mother;
• adults lacking capacity to consent

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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43 participants in 1 patient group

Cognitive multisensory rehabilitation

Experimental group

Description:

The treatment group will receive the cognitive multisensory rehabilitation that uses motor imagery and sensory discrimination exercises

Treatment:

Other: Cognitive multisensory rehabilitation