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Functional Decline and QoL in People Aging with HIV in Asia

The Chinese University of Hong Kong logo

The Chinese University of Hong Kong

Status

Completed

Conditions

Frailty
HIV/AIDS
Disability Physical

Study type

Observational

Funder types

Other

Identifiers

NCT04212884
Geri_HIV_protocol_v4_26Nov2019

Details and patient eligibility

About

This is a multi-center prospective cross-sectional study to determine the burden of decline in intrinsic capacity and functional ability, and the prevalence of geriatric syndromes, such as frailty, and disability in adult people living with HIV (PLWH) in Asia.

Full description

This research project is expected to have the following clinical impact

  1. To understand the impact of impaired functional status in PLWH in Asia would be important to determine the long-term health burden needs in this aging population in this part of the world.
  2. The identification of risk factors associated with impaired functional status would be important to guide clinical decisions in patient management, such as the choice of anti-retroviral regimen, and screening of and early intervention for modifiable risk factors. These are of paramount importance in the promotion of healthy aging in this population.
  3. This proposed cross-sectional study lays the foundation for the establishment of a longitudinal cohort for long-term follow up of people aging with HIV in Asia, with the objectives of evaluating the long-term impact of aging on clinical outcomes and functional status in PLWH in this region.

Enrollment

1,500 patients

Sex

All

Ages

35+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • HIV antibody positive
  • Age 35 years or above
  • Asian ethnicity, including but not limited to Chinese, Malay and Indian

Exclusion criteria

  • Inability or refusal to consent
  • Active infections requiring in-hospital treatment

Trial design

1,500 participants in 2 patient groups

PLWH
Description:
PLWH followed up at the five participating HIV centers
HIV-uninfected individuals
Description:
Age and sex-matched HIV-uninfected individuals

Trial contacts and locations

2

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Central trial contact

Rity Wong; Catherine Cheung, MPhil

Data sourced from clinicaltrials.gov

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