Functional Epiphora Management Via Different Dacryocystorhinostomy (DCR) Techniques

Istanbul University

Status: Completed

Conditions: Functional Epiphora (Tearing Without Any Anatomical Block)

Treatments: Procedure: External Dacryocystorhinostomy; Procedure: Transcanalicular Dacryocystorhinostomy; Procedure: Endonasal Dacryocystorhinostomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04952454

1533-2020

Details and patient eligibility

About

135 eyes of 135 patients treated between 2005 and 2017 will be included in this study. The diagnosis of functional epiphora was made based on a patent lacrimal system with a delay in the fluorescein dye disappearance test (FDDT) or dacryoscintigraphy (DSG) without any ocular surface or eyelid abnormalities. The absence of epiphora and normalization of FDDT postoperatively was defined as success. The study's hypothesis is that external DCR with a suitable technique will have better results compared to endonasal and transcanalicular DCR

Enrollment: 135 patients

Sex

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patent lacrimal irrigation and delay in the lacrimal transit time demonstrated by fluorescein dye disappearance test (FDDT) or a dacryoscintigraphy (DSG)

Exclusion criteria

• Dry eye (tear break up time less than 10 seconds), ocular surface disorders, eyelid malposition or laxity, orbicularis weakness, partial block or stenosis of the lacrimal drainage, history of previous nasal, lacrimal, or ophthalmic surgeries, and a postoperative follow-up time less than six months

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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135 participants in 3 patient groups

External DCR

Active Comparator group

Description:

Patients treated with External DCR for functional epiphora

Treatment:

Procedure: External Dacryocystorhinostomy

Endonasal DCR

Active Comparator group

Description:

Patients treated with Endonasal DCR for functional epiphora

Treatment:

Procedure: Endonasal Dacryocystorhinostomy

Transcanalicular DCR

Active Comparator group

Description:

Patients treated with Transcanalicular DCR for functional epiphora

Treatment:

Procedure: Transcanalicular Dacryocystorhinostomy