Functional Inspiratory Muscle Training in Obese Individuals

Biruni University

Status: Enrolling

Conditions: Obesity

Treatments: Other: Functional Inspiratory Muscle Training; Other: Aerobic+Resistive Exercise Traning

Study type: Interventional

Funder types: Other

Identifiers

NCT06280183

323132

Details and patient eligibility

About

In obese individuals, increased adipose tissue and systemic inflammation play a key role in the development of cardiometabolic diseases, pulmonary system dysfunction, and many respiratory diseases. Existing research has demonstrated beneficial clinical outcomes of inspiratory muscle training or combined aerobic and resistance exercise training in obese individuals. However, this focused on the isolated effects of exercise on obesity. In the current literature, no study is evaluating the effectiveness of functional inspiratory muscle training in obese individuals.

This study aims to investigate the effects of functional inspiratory muscle training on body composition, cardiometabolic markers, functional capacity, respiratory function, respiratory muscle strength, and respiratory muscle performance in obese individuals.

Full description

Obesity is characterized by increased adipose tissue and systemic inflammation that play a key role in the development of non-communicable chronic diseases. It is well known that individuals with obesity have decreased exercise capacity and muscle weakness in both peripheral and respiratory muscles.

Exercise training is recommended in addition to healthy dietary habits in managing obesity. Current literature demonstrated beneficial clinical outcomes of isolated inspiratory muscle training or combined aerobic and resistance exercise training in obese individuals.

Functional inspiratory muscle training is a method that combines both aerobic exercise and inspiratory muscle training. In the current literature, no study is evaluating the effectiveness of functional inspiratory muscle training in obese individuals. The aim of this study is to investigate the effect of functional inspiratory muscle training on body composition, cardiometabolic markers, functional capacity, respiratory function, respiratory muscle strength and respiratory muscle performance in obese individuals.

Enrollment: 45 estimated patients

Sex: All

Ages: 25 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Those between the ages of 25-60
• According to the World Health Organization (WHO) classification, those with a body mass index between 30-40 kg/m2
• Volunteering to participate in the research

Exclusion criteria

• According to the World Health Organization (WHO) classification, body mass index is over 40 kg/m2
• Functional class III or IV according to the New York Heart Association (NYHA) classification
• Those with a Charlson comorbidity score of 3 and above
• Uncontrolled hypertension, diabetes and unstable angina pectoris
• Cooperative disorders, orthopedic and neurological problems that may interfere with evaluation and treatment
• Individuals with a history of lower extremity-related injury or surgery in the last six months
• Being diagnosed with diabetes and having complications such as nephropathy, retinopathy and neuropathy
• Those with accompanying chronic respiratory disease
• Those with acute infection
• Individuals with middle ear-related pathologies (such as tympanic membrane rupture, otitis)
• Those with a STOP-Bang score of 3 and above
• Individuals with a history of spontaneous or trauma-related pneumothorax
• Smokers
• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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45 participants in 3 patient groups

Aerobic and Resistive Exercise Training

Active Comparator group

Description:

The exercise program will start with a 5-10 minute warm-up and end with a 5-10 minute cool down. Aerobic exercise is planned at 60-85% of Maximum Heart Rate on the bike for 30-40 minutes. Resistive exercise program, covering all major major muscle groups; The upper body (pectoralis, latissimus dorsi, rotator cuff muscles, deltoid, biceps, triceps), abdominal muscles and lower extremities (quadriceps, hamstring, gastrosoleus) will be exercised to strengthen. For upper body muscles, abdominal muscles and lower extremity muscles, 1-3 sets of 10-15 repetitions will be planned as 40-70% of 1 maximum repetition (1RM).

Treatment:

Other: Aerobic+Resistive Exercise Traning

Functional Inspiratory Muscle Training Group in obese individuals:

Experimental group

Description:

Inspiratory muscle training will be applied simultaneously with aerobic exercise. This program will create the functional IMT. The exercise program will start with a 5-10 minute warm-up and cool down. Aerobic exercise is planned at 60-85% of MHR on the bike for 30-40 minutes, progress will be achieved. Participants will first work with bicycle ergometry and then continue with IMT in the same session for the first three weeks. The intensity of IMT exercise will be set at 40-60% of MIP. After 10 consecutive breathing cycles, participants will be asked to perform 3-4 breath checks. Resistive exercise program, covering all major muscle groups; The upper body (pectoralis, latissimus dorsi, rotator cuff muscles, deltoid, biceps, triceps), abdominal muscles and lower extremities (quadriceps, hamstring, gastrosoleus) will be exercised to strengthen. For upper body muscles, abdominal muscles and lower extremity muscles, 1-3 sets of 10-15 repetitions will be planned as 40-70% of 1RM.

Treatment:

Other: Functional Inspiratory Muscle Training

Control Group:

No Intervention group

Description:

Patient education will be given and no intervention will be made.