Functional MRI Evaluation in Pyeloureteral Junction Syndrome in Children

Central Hospital, Nancy, France

Status: Not yet enrolling

Conditions: Stricture of Pelviureteric Juncture

Treatments: Diagnostic Test: Functional MRI

Study type: Observational

Funder types: Other

Identifiers

NCT05498532

2022PI108

Details and patient eligibility

About

Pyelo-ureteral junction syndrome is the most common urological abnormality in children.

Functional MRI has been evaluated several times, and had shown good correlation with scintigraphy, but tends to over estimate results. Moreover, those studies included a small number of cases. Its sensitivity to detect crossing polar vessel is limited.

We aimed to evaluate, in patients between 0 and 1 year old, the correlation between MRI and scintigraphy differential renal function.

Our secondary objectives are : evaluation of MRI performances to detect polar vessel ; comparison of surgery times depending of MRI only realisation or MRI and scintigraphy realisation.

Enrollment: 270 estimated patients

Sex: All

Ages: 1 day to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children between 0 and 17 years old
• followed for pyelo-ureteral junction syndrome

Exclusion criteria

• none

Trial design

270 participants in 1 patient group

PUJS patients

Description:

Patients between 0 and 17 years old treated or followed for pyelo-ureteral junction syndrome.

Treatment:

Diagnostic Test: Functional MRI