Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness (OxyTarget)

University Hospital, Akershus

Status: Completed

Conditions: Gastrointestinal Diseases; Rectal Diseases; Gastrointestinal Neoplasms; Rectal Neoplasms

Treatments: Procedure: new functional magnetic resonance imaging (MRI) protocols

Study type: Observational

Funder types: Other

Identifiers

NCT01816607

REK-2013/152 (Other Grant/Funding Number)

Details and patient eligibility

About

The purpose of this study is to establish a reliable method for detection of rectal cancer patients with aggressive tumor at risk of metastatic disease and death by functional MRI.

Enrollment: 192 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The patient is willing and able to give full written consent according to the protocol approved by the Regional Ethics Committee.
• The patient has confirmed rectal cancer diagnosis and is scheduled to radical surgery alone or preoperative CRT followed by surgery.
• The patient is ≥ 18 years.
• The patient has no prior rectal cancer treatment.
• The patient has adequate renal function: creatinine clearance ≥ 60 ml/minute.
• The patient has signed the written informed consent according to the protocol approved by the Regional Ethics Committee.

Exclusion criteria

• The patient has contraindication to MRI or MRI contrast agent according to clinical practice.
• The patient wants to withdraw for any reason during the study.

Trial design

192 participants in 1 patient group

Rectal cancer

Treatment:

Procedure: new functional magnetic resonance imaging (MRI) protocols