Functional Organization of Somatosensory Responses in the Secondary Somatosensitive Area and Insula

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Healthy

Treatments: Other: localization

Study type: Interventional

Funder types: Other

Identifiers

NCT00542906

0701023

2007-A00328-45

DGS 2007-0273

Details and patient eligibility

About

The implication of the second somatosensory area (SII) and the insular cortex in the processing of somatosensory inputs is now well established. However the functional anatomy of these areas hidden in the depth of the sylvian scissure remain mostly unknown.

The aim of this fMRI study is to determine the functional cartography of SII and insula. The localization of responses to different somatosensory stimuli (slight touch, warm, cold, heat pain and arthrokinesia) applied on the left hand of 25 healthy volunteers, will be compared.

Full description

Aims : Demonstrate that localization of the several types of somatosensory stimuli is different into SII and into insula. If possible, we'll determine a functional cartography of these areas.

Enrollment: 25 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 25 healthy volunteers will be included ranging in age from 18 to 50 years
• contraception needed for women
• right handed
• All the subjects have to give their written informed consent.

Exclusion criteria

• pregnancy
• neurological or psychiatric disease
• drugs taken <12h before fMRI
• contra-indications to fMRI : pacemaker, clip, metallic device
• Refusing to be informed of the presence of a cerebral abnormality, detected during MRI.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

1

Other group

Description:

healthy volunteers

Treatment:

Other: localization