Functional Outcome After Minimally Invasive Pyeloplasty for Adult Patients With UPJO

Cairo University (CU)

Status and phase: Enrolling; Phase 3

Conditions: Ureteropelvic Junction Obstruction

Treatments: Procedure: pyeloplasty

Study type: Interventional

Funder types: Other

Identifiers

NCT05895422

MD-85-2023

Details and patient eligibility

About

an intervention study on adult patients with uretero-pelvic junction obstruction (UPJO) due to crossing vessels would be managed either through classic dismembered pyeloplasty or vascular hitch.

Full description

in recent studies, some patients with crossing vessels UPJO could be managed by vascular displacement of these vessels, what is named as vascular hitch or vasculopexy in a way to avoid classic dismembered technique. this newer technique is supposed to provide comparable results to the classic technique but with lesser operative time and shorter hospital stay. in the era of minimally invasive procedures, robotic assisted or laparoscopic vascular hitch could provide many advantages over the classic open technique.

Enrollment: 17 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all patients with UPJO above 18 years
• UPJO caused by crossing vessels confirmed by CT angiography
• Symptomatic UPJO

Exclusion criteria

• recurrent UPJO after a previous trial of open repair ,
• secondary UPJO after open renal surgery.
• UPJO in non functioning kidney

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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17 participants in 2 patient groups

vascular hitch

Experimental group

Description:

displacement of the lower polar crossing vessels causing the UPJO

Treatment:

Procedure: pyeloplasty

Dismembered pyeloplasty

Active Comparator group

Description:

classic Anderson-Hynes procedure

Treatment:

Procedure: pyeloplasty