Functional Outcome of Urethral Reconstructive Surgery

Universitaire Ziekenhuizen KU Leuven

Status: Completed

Conditions: Urethral Stricture

Treatments: Procedure: substitution urethroplasty (pedicled skin flap); Procedure: substitution urethroplasty (buccal mucosa); Procedure: end-to-end urethroplasty

Study type: Observational

Funder types: Other

Identifiers

NCT01982136

S55868 (Other Identifier)

ML9859

Details and patient eligibility

About

The analysis of the long-term outcomes and quality-of-life parameters after urethral reconstruction surgery.

Full description

Urethroplasty is the surgical repair of a urethral stricture. Depending on the location, severity and length of the stricture, various techniques can be performed.

The first procedure consists of the excision of the stenotic segment and end-to-end anastomosis. Other procedures consist of widening the urethra with buccal mucosa as free graft or with vascularized (genital) skin flaps. The results of these techniques have been described in prospective cohort studies, but to date there is little good data about the functional outcome and quality-of-life with longer follow-up after this surgery.

The purpose of this study is to prospectively follow patients for functional outcome parameters and quality-of-life to obtain long-term information concerning these surgeries.

Enrollment: 175 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• male
• urethral stricture surgery
• informed consent

Exclusion criteria

• loss of follow-up
• not willing to participate

Trial design

175 participants in 1 patient group

Urethral stricture

Description:

patients requiring surgery for urethral stricture

Treatment:

Procedure: substitution urethroplasty (buccal mucosa)

Procedure: end-to-end urethroplasty

Procedure: substitution urethroplasty (pedicled skin flap)