Functional Prognosis of Post-operative Patients With Cerebral Small Vascular Disease(CSVD)

Shanghai Jiao Tong University

Status: Unknown

Conditions: Long Term Adverse Effects; Cerebral Small Vessel Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT05359588

CSVD2021

Details and patient eligibility

About

The investigators perform a retro-prospective exploratory cohort study among patients 65 to 85 years old with pre-operative head MRI result after thoracic surgery in Renji Hospital Affiliated to Shanghai Jiaotong University from November 2020 to December 2021. Perioperative data were collected, including preoperative general condition, laboratory examination, auxiliary examination (blood routine, blood coagulation, liver and kidney function, etc.), perioperative indicators （use of anesthetics, anesthetic time, blood pressure, etc.）, postoperative cerebral function follow-up and occurrence of cerebral vascular complications (brain infarction, brain bleed, etc.) of patients.

Enrollment: 212 estimated patients

Sex: All

Ages: 65 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 65≤age<85
• after thoracic surgery
• finish pre-operative brain MRI

Exclusion criteria

• mental illness
• existing dementia and other diseases: Alzheimer disease, dementia, Parkinson's disease, Huntington's disease, systemic lupus erythematosus, etc.
• previous cerebral infarction or hemorrhage