Functional Respiratory Imaging of Airways in ARDS

Antwerp University Hospital (UZA)

Status: Completed

Conditions: ARDS, Human

Treatments: Procedure: Repeated CT scan; Device: CT scan

Study type: Interventional

Funder types: Other

Identifiers

NCT03309085

EC 10/52/359

B300201010195 (Registry Identifier)

Details and patient eligibility

About

This is a prospective single-center cohort trial to compare regional bronchial recruitment, bronchial distention and alveolar recruitment in 6 patients with acute respiratory distress syndrome (ARDS). The investigators used CT scan images as the imaging modality, and the subjects were scanned on end-expiratory lung volume with different positive end-expiratory pressures. Those images were post-processed to evaluate the airways.

Enrollment: 7 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• mechanically ventilated
• moderate or severe ARDS, as defined by the Berlin criteria

Exclusion criteria

• pregnancy
• hemodynamic instability
• obesity (BMI >30)

Trial design

7 participants in 1 patient group

Single arm

Experimental group

Description:

Repeated CT scan

Treatment:

Device: CT scan

Procedure: Repeated CT scan