Functional Significance of Complexity Measures in the Sensory-motor Behavior (NEURO COMP)

Centre Hospitalier Universitaire de Nīmes

Status: Completed

Conditions: Healthy Volunteers

Treatments: Drug: Wrist anesthesia; Other: Anti-noise helmet; Other: Blinding mask; Other: Tapping test

Study type: Interventional

Funder types: Other

Identifiers

NCT02610647

LOCAL/2014/ADKT-001

2014-A01257-40 (Other Identifier)

Details and patient eligibility

About

The main objective of this study is to compare between groups the level of complexity of the estimated sensorimotor performance through multi-fractal (minmaxMF-DFA) exponents.

Full description

The secondary objectives of this study are to compare the level of complexity of the estimated sensorimotor performance using the(A) mono-fractal exhibitors (the αDFA values) and the (B) coefficient of variation (CV) between groups.

Enrollment: 60 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The patient must have given his/her informed and signed consent
• The patient must be insured or beneficiary of a health insurance plan
• The subject does not practice music intensively (<1h / day on average)

Exclusion criteria

• The patient is participating in another study
• The patient is in an exclusion period determined by a previous study
• The patient is under judicial protection, or under guardianship
• The patient refuses to sign the consent
• It is impossible to correctly inform the patient
• The patient is pregnant, parturient, or breastfeeding
• The subject regularly practices music
• The subject is suffering from a neurodegenerative disease of the central or peripheral nervous system which may affect the sensorimotor control of rhythmic movements of the upper limb
• The subject has had a recent trauma of the upper limb
• The subject is suffering from uncorrected visual and hearing impairment

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 5 patient groups

Control group

Other group

Description:

Subjects randomized to this group will have a tapping test with no sensory blocking. Intervention: Tapping test

Treatment:

Other: Tapping test

Wrist anesthesia

Experimental group

Description:

Subjects randomized to this group will have an axillary block / regional anesthesia followed by a tapping test. Intervention: Wrist anesthesia Intervention: Tapping test

Treatment:

Other: Tapping test

Drug: Wrist anesthesia

Wrist anesthesia, masked

Experimental group

Description:

Subjects randomized to this group will have an axillary block / regional anesthesia, will wear a blinding mask, and then will perform a tapping test. Intervention: Wrist anesthesia Intervention: Blinding mask Intervention: Tapping test

Treatment:

Other: Tapping test

Other: Blinding mask

Drug: Wrist anesthesia

Wrist anesthesia, helmet

Experimental group

Description:

Subjects randomized to this group will have an axillary block / regional anesthesia, will wear an anti-noise helmet, and then will perform a tapping test. Intervention: Wrist anesthesia Intervention: Anti-noise helmet Intervention: Tapping test

Treatment:

Other: Tapping test

Other: Anti-noise helmet

Drug: Wrist anesthesia

Wrist anesthesia, masked & helmet

Experimental group

Description:

Subjects randomized to this group will have an axillary block / regional anesthesia, will wear a blinding mask, will wear an anti-noise helmet, and then will perform a tapping test. Intervention: Wrist anesthesia Intervention: Blinding mask Intervention: Anti-noise helmet Intervention: Tapping test

Treatment:

Other: Tapping test

Other: Blinding mask

Other: Anti-noise helmet

Drug: Wrist anesthesia