Functional Yogurt Consumption and Its Effects on the Lipid Profile of Healthy Subjects (FYOPO)

Pontificia Universidad Javeriana

Status: Completed

Conditions: Functional Food; Apolipoproteins; HDL; Cardiovascular Diseases; Low-density-lipoprotein-type; Triglycerides; Food Preferences

Treatments: Other: Sacha inchi oil yogurt; Other: Hybrid palm oil yogurt; Other: Control yogurt

Study type: Interventional

Funder types: Other

Identifiers

NCT06574711

20415

Details and patient eligibility

About

The purpose of this study was to assess the effect of the daily intake of yogurts enhanced with Sacha Inchi oil and hybrid palm tree oil on human plasma lipids related to cardiovascular risk factors

Full description

After being recruited and signing a written informed consent about the study and potential risks, the participants were randomized and assigned in a double-blind manner to one of three intervention groups (control yogurt, sacha inchi oil yogurt, or hybrid palm tree oil yogurt; consumption 1 bottle of 200ml per day for 90 days.

Enrollment: 54 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal total cholesterol (≤200mg/dl) levels
• Have a yogurt consumption habit of at least three times a week
• Maximum level of moderate physical activity
• Body mass index (BMI) of ≤29.9kg/m2
• Serum triacylglycerols below 400mg/dl

Exclusion criteria

• Presence of chronic disease (Arterial hypertension, Diabetes Mellitus, among others)
• A history of illicit drug use and/or chronic alcohol use, active smoking
• A well-established allergy to red palm olein and/or milk and its derivatives
• Consumption of nutritional supplements (antioxidants, omega 3, fiber, phytosterols)
• Pregnancy or lactation
• Having menopause
• High consumption of nuts, flaxseed, chia, and sesame seeds

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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54 participants in 3 patient groups, including a placebo group

Control yogurt

Placebo Comparator group

Description:

Participants consumed a 200 g bottle of plain Yogurt with 3.5% unreplaced fat orally, daily, for 90 days

Treatment:

Other: Control yogurt

Sacha inchi oil yogurt

Experimental group

Description:

Participants consumed a 200 g bottle of Yogurt with 3.5% replacement of dairy fat for Sacha inchi oil, orally, daily, for 90 days

Treatment:

Other: Sacha inchi oil yogurt

Hybrid palm oil yogurt

Experimental group

Description:

Participants consumed a 200 g bottle of Yogurt with 3.5% replacement of dairy fat for Hybrid Palm Oil, daily, for 90 days

Treatment:

Other: Hybrid palm oil yogurt