Future Optimal Research and Care Evaluation - Aortic Stenosis (FORCE-AoS)

St. Antonius Hospital

Status: Enrolling

Conditions: Severe Aortic Valve Stenosis; Moderate Aortic Valve Stenosis

Treatments: Behavioral: Quality of life questionnaires will be assessed in addition to standard care

Study type: Observational

Funder types: Other

Identifiers

NCT06168123

Z23.069

Details and patient eligibility

About

In the past decade the treatment of aortic valve stenosis has rapidly changed. At first, transcatheter aortic valve implantation (TAVI) was a last resort option for inoperable patients. Nowadays, it more and more becomes an alternative to surgical aortic valve replacement (SAVR) - also in younger and lower risk patients. This poses important questions to clinical practise regarding the optimal life-time management of each individual patient. Which involves (durability of) treatment modality (surgical vs. transcatheter vs. conservative treatment) as well as the duration and type of the required antithrombotic treatment.

Objective: to evaluate the effect of treatment modality (surgical vs. transcatheter vs. conservative treatment) and its complications on quality of life and survival in AoS patients.

Enrollment: 800 estimated patients

Sex: All

Ages: 18 to 110 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Older than 18 years of age
• Severe or moderate aortic stenosis

No exclusion criteria are applicable to this registry