Gabapentin Oral Solution in Decreasing Desflurane Associated Emergence Agitation

Kuwait Specialized Eye Center

Status: Unknown

Conditions: Emergence Agitation After Desflurane Anesthesia

Treatments: Drug: Strawberry juice as (placebo); Drug: Gabapentin Oral Solution [Neurontin]

Study type: Interventional

Funder types: Other

Identifiers

NCT03347916

kuwaiteyecenter01

Details and patient eligibility

About

to study the effect of oral gabapentin (5 mg/kg) on emergence agitation after desflurane anesthesia in pediatrics undergoing starbismus surgery

Enrollment: 75 estimated patients

Sex: All

Ages: 2 to 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pediatric patients (2-6 years old), with an American society of Anesthegiologists physical status (ASA) I-II who were undergoing strabismus surgery (for more than one muscle)

Exclusion criteria

• failure to obtain consent, mental retardation or developmental delay, epilepsy, psychiatric or neurological diseases that impair communication, current use of gabapentin, psychotropic or opioids.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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75 participants in 2 patient groups, including a placebo group

Control group

Placebo Comparator group

Description:

patients received strawberry juice 5 ml volume, one hour before induction.

Treatment:

Drug: Strawberry juice as (placebo)

Gabapentin group

Active Comparator group

Description:

patients received gabapentin (Neurontin oral solution 250 mg/ml, Pfizer, USA) 5 mg/kg mixed with strawberry juice to constitute 5 ml volume, one hour before induction.

Treatment:

Drug: Gabapentin Oral Solution [Neurontin]