Gait Analysis in MPS IVA

Oregon Health & Science University (OHSU)

Status

Completed

Conditions

Morquio Syndrome

MPS IVA

Study type

Observational

Funder types

Other

Industry

Identifiers

NCT01920828

OregonHSU-8833

Details and patient eligibility

About

The purpose of this study is to learn about gait (walking) characteristics in MPS IVA and possible changes in gait with enzyme replacement therapy.

Full description

The purpose of this 3-year study is to conduct a longitudinal investigation using motion analysis of gait to objectively and quantitatively assess gait characteristics of MPS IVA patients. Data documenting gait characteristics and abnormalities will be gathered in patients initiating enzyme replacement therapy.

Inclusion criteria Individuals with MPS IVA diagnosed by enzyme or molecular studies Exclusion Criteria Individual with MPS IVA previously enrolled in BMN-110 Individual is non-ambulatory The individual is unable to complete longitudinal study visits at least yearly

Enrollment

10 patients

Sex

All

Ages

1+ year old

Volunteers

No Healthy Volunteers

Inclusion criteria

-Diagnosis of MPS IVA

Exclusion criteria

Non-ambulatory