Gait Control in Parkinson Disease (GAIT-PD)

Université Catholique de Louvain

Status: Enrolling

Conditions: Parkinson Disease

Treatments: Other: Walking test; Other: Disease assessement

Study type: Observational

Funder types: Other

Identifiers

NCT05908279

GAIT-PD

Details and patient eligibility

About

Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients and volunteers able to walk for 20mins and without other neurological disorders.

Exclusion criteria

• Patients or volunteers unable to walk for 20mins and with other neurological disorders.

Trial design

100 participants in 2 patient groups

PD

Description:

Patients with Parkinson's disease

Treatment:

Other: Walking test

Other: Disease assessement

Control

Description:

Healthy volunteers

Treatment:

Other: Walking test