Gallbladder Cholesterolosis, Body Mass Index and Serum Cholesterol and Triglycerides

Cirujanos la Serena

Status: Completed

Conditions: Gallstones; Gallbladder Cholesterolosis

Treatments: Other: Specimen biopsy and serum laboratory tests

Study type: Observational

Funder types: Other

Identifiers

NCT00528632

HLS-0012-09-07

Details and patient eligibility

About

Cholesterolosis is a common finding in biopsy specimens of gallbladders surgically removed for cholelithiasis.

To the best of the investigators knowledge no study has analyzed the relationships of Body Mass Index, serum Cholesterol and Triglycerides and gallbladder cholesterolosis.

The purpose of this study is to analyze and find relations between gallbladder cholesterolosis, Body Mass Index, serum cholesterol and triglycerides.

Full description

A prospective database including the following variables was filled out:

• Age
• Gender
• Diagnosis
• Weight
• Height
• Body Mass Index
• Histopathological results (Biopsy)
• Serum cholesterol
• Serum triglycerides

All elective patients older than 15 years of age submitted to cholecystectomy for symptomatic gallstones were included. Plasma cholesterol and triglycerides levels were measured 5 to 7 days before surgery. Only patients with chronic cholecystitis and with cholesterolosis according to the histology of the surgical specimen were included, we did not include any patient with acute cholecystitis or gallbladder cancer.

Enrollment: 406 patients

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients submitted to elective cholecystectomy
• Histopathological report of gallbladder cholesterolosis
• Histopathological report of chronic cholecystitis
• Patients older than 15 years of age

Exclusion criteria

• Patients younger than 15 years of age
• Pathological report missing from the hospital records

Trial design

406 participants in 2 patient groups

Cholesterolosis

Description:

I. Patients with gallbladder cholesterolosis and symptomatic cholelithiasis

Treatment:

Other: Specimen biopsy and serum laboratory tests

Cholelithiasis

Description:

II. Patients without gallbladder cholesterolosis and with symptomatic cholelithiasis

Treatment:

Other: Specimen biopsy and serum laboratory tests